Expression levels of miR-205, -141, -203,and -15b were lower, whereas expression of miR-9 was higher in melanoma tissue.Interestingly, miR-9, -15b, and -203 are documented to contributeto BRAF pathways by directtargeting of RAF, MEK, and ERK. Moreover, miR-9 and -141are associated with stemness properties by targeting SOX2 andOCT4. The gene discussed is SOX2; the disease is melanoma.