Additionally, gAd could also suppress the expression levels of cleaved caspase-3, RIP1, and RIP3 after I/R treatment, which confirms that gAd inhibits both apoptosis and necroptosis in the myocardial ischemia/reperfusion injury in vivo (Figures 7(b)–7(e)). This evidence concerns the gene CASP3 and myocardial ischemia.