The results indicated that the members of the MAGE family, including MAGEB10, MAGED2, TRO, MAGEH1, MAGEB18, MAGEB6, MAGEB4, MAGEB1, MAGED4B, MAGED1, MAGEB2, and MAGEB3, were significantly overexpressed in sarcoma tissues. The gene discussed is MAGEB4; the disease is sarcoma.