Furthermore, MIR-675-3p, MIR-675-5p, VEGF, and ICAM1 were positively expressed with H19. These results suggest that atorvastatin increases the secretion of H19 exosomes by rat mesenchymal cells, activates VEGF and ICAM1 by regulating the expression of MIR−675-3p and MIR−675-5p, and promotes angiogenesis in the endothelium after myocardial infarction (59). The gene discussed is VEGFA; the disease is myocardial infarction.