Besides, cytokine-cytokine receptor interaction signaling pathway, calcium signaling, TGF-β signaling pathway, Jak-STAT signaling pathway, focal adhesion signaling pathway, HIF-1signaling pathway may also be potential pathways for differentially expressed circRNAs to regulate the pathological process of endothelial injury and atherosclerosis (Figure 7). Here, SOAT1 is linked to atherosclerosis.