In addition, MKK6 and TP53RK, the potential targets of miR-30d-3p and miR-140-3p, were up-regulated in atherosclerotic vessels and oxidative-stress damaged endothelial cells, further suggesting that circRNA KHDRBS1 and circRNA ABCA1 may regulate vascular endothelial injury and atherosclerosis through the ceRNA mechanism. This evidence concerns the gene KHDRBS1 and atherosclerosis.