We analyzed these microRNAs and selected those that have the possibility to regulate atherosclerosis and evolutionarily conserved, including, miR-30d-3p and miR-140-3p, which had conserved binding sites with mmu_circRNA_37699 (circRNA KHDRBS1) and mmu_circRNA_36781 (circRNA ABCA1). The gene discussed is KHDRBS1; the disease is atherosclerosis.