Among them, the K-RAS G12C oncogenic mutation is present in about 3–14% of cancer patients (Prior et al., 2012; Prior et al., 2020; Nassar et al., 2021) and has been targeted for drug discovery efforts (Ostrem et al., 2013; Lito et al., 2016; Janes et al., 2018; Hallin et al., 2020; Moore et al., 2020). Here, KRAS is linked to cancer.