ARPC3 and hepatocellular carcinoma: We used the CCLE databases to probe the mRNA expression of Arp2/3 subunits in HCC cell lines and found that Arp2/3 subunits were widely expressed in 23 HCC cell lines; among them, the expression levels of ACTR2 and ARPC3 were higher than those of other subunits, and the ARPC5L expression level was lowest in HCC cell lines (Figure 4).