The results revealed that the mRNA expressions of Arp2/3 subunits were correlated to a significant degree in HCC tissues, such as ARPC1A and ARPC1B (Pearson’s R = 0.65), ARPC2 and APRC3 (Pearson’s R was 0.6), ARPC2 and ACTR (Pearson’s R was 0.66), ARPC3 and ARPC4 (Pearson’s R was 0.65), ARPC3 and APRC5L (Pearson’s R was 0.64), ARPC4 and ARPC5L (Pearson’s R was 0.64), and ARTC2 and ARTC3 (Pearson’s R was 0.83), as shown in Figure 5. The gene discussed is NCOA3; the disease is hepatocellular carcinoma.