HSP90AA1 and colorectal cancer: The univariate analysis showed that the biomarkers as CA125, CEA, CA199 and HSP90α were associated with metastasis in colorectal cancer patients, and the multivariate analysis revealed that the biomarkers as CEA, CA199 and HSP90α were independent risk factor for distant metastasis in patients with colorectal cancer (all p < 0.001).