TAS2R38 and respiratory tract infectious disorder: Therefore, other bitter taste receptor, among which TAS2R14 and TAS2R20, which in the present work we have discovered to be activated by vanillin, have been identified to respond to several bacterial acyl homoserine lactones (41) and quinolones (42), making them potential therapeutic target for upper respiratory infections treatments, particularly in TAS2R38 AVI/AVI individuals (43).