In macrophages of patients with IgA nephropathy and macroscopic hematuria-related AKI, CD163 was associated with incomplete recovery of kidney function (152, 155) describing as the predominant subpopulations in kidney tissues, the M2a (CD206+/CD68+) and M2b (CD86+/CD68+) macrophages (130). This evidence concerns the gene MRC1 and IgA glomerulonephritis.