MALAT1 and colorectal cancer: When we carefully evaluated the history of 17 patients (15 patients with liver metastases within 5 years of initial diagnosis vs. the five patients without any metastases within 5 years of initial diagnosis), we found a clear correlation of a positive signature (downregulated LOC285194, upregulated HOTAIR and MALAT1) with colorectal cancer progression (Table 2).