Elevated NE levels lead to the abnormal phosphorylation of Src through ADRB2, followed by regulation of downstream pathways to enhance the proliferation, migration, and angiogenesis of ovarian cancer cells (Nilsson et al., 2007; Sood et al., 2010; Armaiz-Pena et al., 2013; Choi et al., 2015; Cole et al., 2015). This evidence concerns the gene ADRB2 and ovarian cancer.