FOCAD and non-small cell lung carcinoma: Besides, Liu et al. (2020) found that the transcription factor nuclear factor-erythroid 2-like 2 (NRF2) inhibitor (Brusatol) could enhance the sensitivity of NSCLC cells to cystine deprivation-induced ferroptosis by FOCAD-FAK signaling, and the combination use of Brusatol and erastin showed better therapeutic action against NSCLC.