Prince et al. (2007) published that CD44+ tumor cells usually make up < 10% of all cells in the entirety of HNSCC. The percentage of CD44+ cells within HNSCC is subject to inter-individual fluctuations. Here, the proportion of CD44+ cells varied from 4% to over 90% (Pries et al., 2008). This evidence concerns the gene CD44 and head and neck squamous cell carcinoma.