CD8A and neoplasm: Considering that higher T-cell exhaustion markers indicating a CD8 + T-cell-related tumor-promoting microenvironment and CD8 + T cells exert antitumor activity through Treg cell regulation (Xiao et al., 2020), our data demonstrated that ARHGAP17 and ARHGAP24 correlated with CD8 + T cells and Treg cell infiltration and function in BCa microenvironment.