In Korea, an additive effect of single nucleotide polymorphisms (SNPs) was noted in the patatin-like phospholipase domain containing three genes (PNPLA3) and transmembrane six superfamily 2 (TM6SF2) that affect the severity of liver damage as reported in adult patients with NAFLD (43). Here, PNPLA3 is linked to metabolic dysfunction-associated steatotic liver disease.