The SNPs in the region of IFN-λ are associated with the standard treatment response for chronic hepatitis C as well as with the spontaneous HCV clearance (Thomas et al., 2009), as IFNL3 SNPs, are considered the strongest predictors upon antiviral therapy response (Cavalcante and Lyra, 2015). This evidence concerns the gene IFNL3 and chronic hepatitis C virus infection.