Other studies with CHC patients treated with Peg-IFN-α/Ribavirin from different regions in Brazil focused on the SNPs rs12979860 and rs8099917, evidencing that CC and TT genotypes, respectively, presented favorable treatment outcomes (Ge et al., 2009; Thomas et al., 2009; Cavalcante et al., 2012; Ramos et al., 2012; Moreira et al., 2016; Rizzo et al., 2016). The gene discussed is IFNA1; the disease is cryohydrocytosis.