The results showed that LDHA expression was significantly elevated in breast invasive carcinoma, COAD, esophageal carcinoma, head and neck cancer, kidney renal clear cell carcinoma, lung adenocarcinoma, lung squamous cell carcinoma, prostate adenocarcinoma, rectum adenocarcinoma, stomach adenocarcinoma, and uterine corpus endometrial carcinoma compared with adjacent normal tissues, and decreased in kidney chromophobe, which also established that there was a high LDHA expression in COAD (Figure 1B). This evidence concerns the gene LDHA and colon adenocarcinoma.