AFP and neoplasm: In the multivariate regression model I (Table 2), AFP levels higher than 400 ng/mL were found to be the best predictors for positive MVI with an odds ratio (OR) value of 5.12, followed by CEUS LR-M (OR=3.80), 20 ng/mL<AFP level<400 ng/mL (OR=3.11) and tumor size larger than 30 mm (OR=2.86).