Especially, this SRC gene can be synergistically inhibited by miR-125b-5p, miR-99a-5p, miR-139-3p, miR-139-5p (Figure 4A and Tables S3, S4), and thus their down-regulation expressions can cause the up-regulation expression of SRC to further lead to a poorer prognosis for HCC patients (p = 0.01) (Figure 4B). The gene discussed is SRC; the disease is hepatocellular carcinoma.