A previous study had demonstrated that the overexpression of FOXO1 can significantly increase the expression levels of many target miRNAs (e.g. miR-125b, miR-99, miR-101, miR-let-7c, miR-675, miR-199a) to suppress nasopharyngeal carcinoma cell proliferation (76). This evidence concerns the gene FOXO1 and nasopharyngeal carcinoma.