In particular, cancer cells carrying the translocation t(4; 14) seem to have a greater expression of SLAMF7 and the in vitro inhibition of the expression of SLAMF7 in these cells is able to reduce the formation of colonies and to induce apoptosis and arrest of cells in G1, thus indicating an important role of this receptor in the proliferation of MM cells (88). The gene discussed is SLAMF7; the disease is cancer.