In vitro, EM801 induces a strong, dose dependent bond between T lymphocytes and MM cells with consequent activation of T cells, documented by the hyper-expression of CD25 and CD69 and release of granzyme B and inflammatory cytokines such as IFNγ, TNFα, and IL-2 (Figure 3). The gene discussed is IFNG; the disease is Miyoshi myopathy.