Since cancer‐associated genes might be crucial for stem cell fitness due to the shared molecular programs between somatic reprogramming, cancer progression, and organ regeneration,[10, 11, 17, 18, 19, 21, 36] an shRNA library targeting 700 potential “cancer genes” was included.[37] FACS‐based separation/sorting of reprogrammed (repro) stage‐specific embryonic antigen‐1 (SSEA1)‐positive (iPSC) and non‐reprogrammed (non‐repro) SSEA1‐negative cells (non‐iPSC) allowed retrieval of genomic DNA of distinct populations. The gene discussed is FUT4; the disease is cancer.