CD4 and type 1 diabetes mellitus: Furthermore, mice with transplanted organoids did not develop T1D; however, 53% of the controls developed T1D.[74] In addition, Tregs produced from mESC‐derived TECs have shown to be capable of preventing chronic graft versus host disease (cGVHD).[75] Organoids productively formed working Tregs, which could accept allogenic grafts by suppressing CD4+ and CD8+ DP cells.