In another retrospective cohort study, preexisting hypertension, moderate or severe ARDS, lymphocyte counts of <0.5 × 109/L, albumin of <22 g/L, procalcitonin of >0.2 ng/mL, D-dimer of >1200 ng/mL, and the need for continuous renal replacement therapy were associated with higher mortality in ICU patients [36]. The gene discussed is ALB; the disease is acute respiratory distress syndrome.