Furthermore, we used complex statistical methods to analyze the RBPs related to the prognosis of ccRCC patients and finally obtained 9 RBPs, namely, RPL36A, THOC6, RNASE2, U2AF1L4, TLR3, PPARGC1A, DARS, LARS2, and NOVA2, most of which have been reported in detail in terms of the roles in kidney cancer and other tumors. The gene discussed is TLR3; the disease is kidney cancer.