As displayed in Figure 8(b), TP53, AKT1, SRC, STAT3, MAPK3, PIK3CA, MAPK1, PIK3R1, HRAS, JUN, VEGFA, HSP90AA1, EGFR, JAK2, MAPK8, and JUN could be the potential target genes for KCMMs in the treatment of HCC. This evidence concerns the gene PIK3CA and hepatocellular carcinoma.