These herbal effects on ICCs and SCF have also been reported in other animal models, including in a trinitrobenzene sulfonic acid-induced rat colitis model treated with Shenqing recipe [40], a cirrhotic ascites rat model treated with Xiaozhang Tie [55], and a loperamide-induced constipation rat model treated with Herba Cistanche [56]. The gene discussed is KITLG; the disease is constipation disorder.