TNF and erythema multiforme: In addition, Bushen Zhuyu decoction (BSZYD) is 94.12% effective in treating EM, and IL-6, IL-8, and TNF-α levels are significantly reduced after treatment, indicating that BSZYD can improve EM dysmenorrhea and the pelvic microcirculation of patients with dysmenorrhea, regulate the expression level of related factors, and relieve pain [37].