In our analysis of the relationship between HOXBs and a variety of traditional tumor drug targets, we found that HOXB5/7/9/13 were positively correlated to CCT036477 drug targets; HOXB7/8/9/13 were closely correlated to tretinoin, KW-2449, doxorubicin, and SB-225002; and HOXB9 was positively correlated to PX-12 drug activity. Here, HOXB9 is linked to neoplasm.