PPAR-γ is known as an “energy balance receptor” and is a crucial regulator of many PPRE-containing genes such as FABP4 and CPT1A having an essential function in fat metabolism and lipogenesis, resulting in the decline of the circulating blood lipids and inhibition of the liver steatosis [6, 14–17]. The gene discussed is PPARG; the disease is Hepatic steatosis.