The Kaplan-Meier OS analysis indicated that CD161 is a protective factor for patients with ACC, BRCA, CESC, CHOL, HNSC, LIHC, MESO, PRAD, PCPG, SARC, SKCM, and THCA and a risk factor for patients with UVM and LGG. Here, KLRB1 is linked to adrenal cortex carcinoma.