For DSS, the results of univariate Cox regression analysis revealed that CD161 acts as a protective factor for patients with ACC, BRCA, CESC, CHOL, HNSC, LIHC, LUAD, READ, SARC, SKCM, and THCA and a risk factor for patients with ESCA, LGG, and UVM. This evidence concerns the gene KLRB1 and adrenal cortex carcinoma.