SIGMAR1 and cardiac hypertrophy: Sigmar1 activation using agonists has been shown to elicit cardioprotection in these rodent models of cardiac hypertrophy and heart failure (Bhuiyan and Fukunaga, 2009, 2011; Bhuiyan et al., 2010, 2011a,b, 2013; [citeskum]BR294,BR293,BR295,BR297,BR291,BR292[citeekum]Tagashira et al., 2010, 2011, 2013b, 2013c, 2013a, 2014a, Tagashira and Kobori, 2013).