Interestingly, increased cerebral microvasculature of a mice model of type 1 diabetes with a longer duration is immature with a decrease in VEGF-A, Ang-1, PDGF-β, and TGF-β mRNA levels (Poittevin et al., 2015), which is in contrast to our findings. The gene discussed is VEGFA; the disease is type 1 diabetes mellitus.