Melanoma, NSCLC (PD-L1 ≥ 1%), NSCLC (PD-L1 ≥ 50%), SCLC, HNSCC, Hodgkin's lymphoma, primary mediastinal B-cell lymphoma, urothelial cancer, colorectal cancer, gastric cancer, esophageal cancer, cervical cancer, HCC, Merkel cell carcinoma, cutaneous squamous cell carcinoma. The gene discussed is CD274; the disease is head and neck squamous cell carcinoma.