Before tumor recurrence, we found that the levels of exhausted, dendritic cell (DC), T helper 2 cell (Th2), and induced regulatory T cell (iTreg) were positively correlated with HIF1A expression, while those of NK, natural killer T cell (NKT), CD8_T, CD8-naive, and γδ T cell (gamma-delta) were negatively correlated with HIF1A expression (Figure 4C). Here, CD8A is linked to neoplasm.