CASP3 and malignant colon neoplasm: It was revealed in the study by Hassan et al. (2021) that the administration of thymol (20 mg/kg/day, p. o.)in male Wistar rats provided promising protective activity against colon cancer by significantly reducing elevated serum levels of colon-related tumor markers, carbohydrate antigen 19-9 (CA 19-9) and carcinoembryonic antigen (CEA), as well as the apoptotic marker, caspase-3 compared to the colon cancer group.