PPP2R2A and neoplasm: DAPK1 is a serine/threonine kinase, a tumor suppressor protein that promotes apoptosis (Agodi et al., 2015; Zhai et al., 2019), while PPP2R2A, a regulatory subunit of protein phosphatase 2A (PP2A), controls the pathway of AKT signaling associated with tumor growth (Wang et al., 2016; Zeng et al., 2016).