Most recently, Neidhardt et al. (Neidhardt et al., 2019) reported a 2-fold increase of D315 cl-caspase-9 in myocardial biopsies from patients with DCM and did not detect increased cl-caspase-3 or cl-caspase-8 expression. The gene discussed is CASP9; the disease is familial dilated cardiomyopathy.