IL17A and chronic obstructive pulmonary disease: After stimulating a human epithelial cell line (16HBE) with induced sputum supernatants (ISS) from HCs, HSs, or COPD patients, significantly higher levels of TSLP were induced by elevated IL-17A from COPD patients, which could be inhibited by anti-IL-17A Ab(antibody), indicating a direct and specific association between IL-17A and TSLP in the airways.