CYP46A1 was found to be ectopically expressed in brain astrocytes in AD and other cell types in mouse models of MS and traumatic brain injury (Bogdanovic et al., 2001; Brown et al., 2004; Teunissen et al., 2007; Cartagena et al., 2008). The gene discussed is CYP46A1; the disease is Alzheimer disease.