AQP4 expression was positively correlated to the regulator of G protein signaling 5 (RGS5), transcriptional factor Nrf2, long non-coding RNA (lncRNA) MALAT1, and caveolin-1 (Cav-1) after ischemic stroke (Özen et al., 2018; Liu et al., 2019; Filchenko et al., 2020; Wang et al., 2020). Here, CAV1 is linked to ischemic stroke.