Moreover, mutations in the human SNc stable gene SEZ6 have been implicated in diseases such as Alzheimer’s (Khoonsari et al., 2016; Paracchini et al., 2018), childhood-onset schizophrenia (Ambalavanan et al., 2016), epilepsy and febrile seizures (Yamada et al., 1990; Mulley et al., 2011). Here, SEZ6 is linked to epilepsy.