EGFR and neoplasm: Pereira et al. found that statins temporarily modulated the epidermal growth factor receptor (EGFR) and prostate specific membrane antigen (PSMA) on the surface of tumor cells, which enhanced the tumor-binding avidity of the monoclonal antibodies panitumumab, cetuximab and huJ591, thereby synergizing with the antitumor effects of these agents [302].