Although a significant difference between TP53 signature status was not shown in ER negative subtype, luminal A like group (ER positive and Ki-67 < 10%) and triple negative breast cancer (TNBC) group, no recurrent cases was observed in TP53 wild-type signature group (Fig. 4b, c, e). The gene discussed is MKI67; the disease is triple-negative breast carcinoma.