Minor alleles, whose frequencies are reported to be around 50%, in some cases, were more often observed than the major alleles, i.e. AGT rs699:C in PD-NCI, AGTR2 rs5194:A in PD-MCI (men and women) and PDD (women), AGTR2 rs1403543:G in PD-MCI (men), PD-NCI (women), PDD (women), ACE I/D in all three groups. Here, AGTR2 is linked to Parkinson disease.