HF diet-fed WT mice showed upregulation of essential genes associated with FAS (e.g., Scd-1, Fasn) compared to low-fat diet-fed counterparts (Supplementary Fig. 3A, B) without altering the expression of FAO genes (e.g., Cpt1a, Acadvl) (Supplementary Fig. 3C, D). The gene discussed is FAS; the disease is hydrops fetalis.