In comparison, the most common chromosomal aberrations reported in HCC are the gains of 1q (suggested target genes include WNT14, FASL) and 8q (MYC, WISP1) and the loss of 17p (TP53, HIC1), followed by losses of 4q (LEF1, CCNA) and 13q (RB1, BRCA3) [42, 43] (Fig. 3E). Here, WNT9A is linked to hepatocellular carcinoma.