Among the 42 independent loci with rare variants (MAF < 0.050), one locus (i.e., the PGM1 locus) has been reported of association with T1D by previous GWAS studies (Supplementary Data 5, GWAS Catalog, https://www.ebi.ac.uk/gwas/) and two recent large-scale T1D GWAS14,15, thus was not taken as an unreported locus. This evidence concerns the gene PGM1 and type 1 diabetes mellitus.