(2) The association signal in low T1D GRS [Fig. 3a, lack of significance in all T1D patients (Fig. 3b)], tagged by the SNP rs13147255 with OR(95% CI) = 1.318(1.198,1.449), P = 1.42E − 08, at the chr4q28.1 locus, resides between the long intergenic non-protein coding RNA 2516 gene (LINC02516) and the ankyrin repeat domain 50 genes (ANKRD50). Here, ANKRD50 is linked to type 1 diabetes mellitus.