Consistent with increased tumor-infiltrating lymphocytes (TILs) in tumors, CA170 plus KVax treatment also increased the expression of IFN-γ, TNFα, and granzyme B in tumor-infiltrating CD4+ (Figs. 4A and C) and CD8+ (Figs. 4B and D) T cells in tumors. Here, CD8A is linked to neoplasm.