Anakinra treatment normalized (Atf3, Atp2a2, Fhl1, Fosl2, Gng2, Itp1, Lamc3, Mafb, Maff, Myl2, Nlcr3, Pth1r, Tnnc1, Tpm3, Ucp2) and attenuated (Csrp3, Cyfip2) gene expression in muscle from CKD mice (Fig. 8). Here, GNG2 is linked to chronic kidney disease.