FASLG and autosomal dominant polycystic kidney disease: Unguided GSEA correlated previously defined hallmark gene sets to CD178; with Epithelial Mesenchymal Transition (EMT) being the most significantly correlated hallmark gene set (FDR = 1.79 × 10–11), supporting the previously described role of EMT in ADPKD cystogenesis (Fig. 4b)16,39.